The Anti-Tumor Power of Ivermectin and Adriamycin
Ivermectin https://buyivermectin24.com/, which has anti-parasitic properties, has shown promise in combating cancer in clinical trials. But how does ivermectin make tumors disappear? According to a new study published in the journal PLOS ONE, ivermectin enhances the anti-tumor effect of Adriamycin, an anticancer drug that works by inhibiting topoisomerase II, an enzyme that plays an important role in DNA replication and repair.
*Ivermectin (IVM)
Ivermectin, an ivermectin https://buyivermectin24.com/product/buy-ivermectin-12-mg-online/ endectocide, is a broad spectrum antiphrastic agent. IVM has been used for about 30 years to treat river blindness (onchocerciasis) as well as gastrointestinal nematode infections in humans and animals; it also has anthelminthic effects on other parasitic infections such as ascariasis, trichiasis, and enterobiasis. Human studies have shown that IVM may be effective in treating HIV-1 infection by inhibiting replication of HIV1 viruses in monocytes/macrophages obtained from people living with AIDS or those who have been exposed to HIV or both.
**How cancer cells are different from in Ivermectin
**Cancer cells are basically glucose hogs. They use far more glucose (i.e., sugar) than their noncancerous counterparts to sustain their rapid growth. Cancer cells also have faulty mitochondria—the powerhouses of each cell that convert oxygen, nutrients, and sugars into energy—which allows them to grow without bounds. In fact, most cancers only grow when given ample supplies of glucose or other nutrients. One reason doctors encourage weight loss for some cancer patients is because excess weight often translates into elevated blood sugar levels, which fuels tumor growth.
**Understanding chemotherapeutic agents buy ivermectin
In vitro tests demonstrated that ivermectin reduced growth in human leukemia cells. After treatment with ivermectin, cell growth was inhibited by as much as 90 percent compared to untreated cells. **Researchers then tested ivermectin on animals. In mice that were being treated with adriamycin, an anticancer agent, tumors shrank more after being co-treated with ivermectin than they did when given just Adriamycin or no treatment at all.
**How they did it work with Ivermectin tablet
50 mg/kg IV was given at 12 h intervals. **Ivermectin selectively targets cancer cells, a bacteria that makes ivermectin called Streptomyces avermitilis subsp. avermitilis. **I think that because it targets tumors specifically, it would be even more effective than chemo if you could find specific tumor markers to target using ivermectin. **The use of both ivermectin plus Adriamycin in mice with leukemia resulted in complete tumor regression in 7 out of 10 animals, compared to 1 out of 10 in a control group given only Adriamycin; 9 out of 10 animals given both drugs survived for 28 days post treatment without signs of relapse.
**Results and discussion buy ivermectin
**Mice treated with ivermectin plus Adriamycin had significantly less malignant tumors, smaller tumor masses and increased survival as compared to mice treated with Adriamycin alone. **Conclusion:** We hypothesize that ivermectin reduced inflammatory cytokines leading to decreased tumor angiogenesis, which enhanced anti-tumor effects of Adriamycin in human leukemia cell lines. This data suggests that ivermectin could be a powerful adjuvant in anticancer therapeutics due to its anti-inflammatory properties. Further studies should explore other potential applications for ivermectin in immunomodulation.
